Table 2.
Baseline (Awake) | Baseline (Urethane) 10-20 min | Formalin 1st phase (0-10 min) | Formalin 2nd phase (10-60 min) | |||||
---|---|---|---|---|---|---|---|---|
FR(d/s) | Ratio(%) | FR(d/s) | Ratio(%) | FR(d/s) | Ratio(%) | FR(d/s) | Ratio(%) | |
Overall | 5.25 ± 0.80 | 0.64 ± 0.24 | 1.14 ± 0.57 | 1.22 ± 0.14 | ||||
Tonic | 5.08 ± 0.80 | 96.65 | 0.64 ± 0.24 | 100.00 | 1.09 ± 0.57 | 95.73 | 1.12 ± 0.14 | 91.99 |
Burst Spike | 0.17 ± 0.03 | 3.35 | 0.00 ± 0.00 | 0.0 | 0.05 ± 0.52 | 4.27 | 0.10 ± 0.01 | 8.01 |
Awake baseline is the spontaneous neural activity of the awake state. Urethane baseline is the spontaneous neural activity under urethane anesthesia. Neural response after formalin injection is divided into the 1st and 2nd phases based on the typical behavioral response of the formalin test which has a quiescent interval between the two peaks of the behavioral pain responses. N = 29 neurons, 6 mice. All values are mean ± SEM. FR: firing rate, ratio: percentage of respective firing modes from the total number of spikes.