TABLE 5.
Acamprosate | Placebo | |||
---|---|---|---|---|
Responders (Mean ± SD) |
Nonresponders (Mean ± SD) |
Responders (Mean ± SD) |
Nonresponders (Mean ± SD) |
|
Days in treatment | 74 ± 22* | 29 ± 32* | 60 ± 30 | 32 ± 31 |
Change in Drinks/drinking day | −1 ± 1 | −1 ± 1 | −1 ± 1 | 1 ± 2 |
Change in drinks/wk | −4 ± 6 | −8 ±6 | 0 ± 0 | −7 ± 15 |
Change in drinks/mo | −18 ± 25 | −32 ± 24 | −2 ± 2 | −28 ± 61 |
Change in percent days abstinent | −1 ± 12 | −27 ± 42 | −1 ± 3 | 9 ± 18 |
Statistically significant difference between acamprosate responders and nonresponders: t = −2.84, P = 0.018; Mann-Whitney: U = 5.0, Z = −2.10, P = 0.036.
All other comparisons between responders and nonresponders were nonsignificant.