. Author manuscript; available in PMC: 2013 Oct 10.

Published in final edited form as: J Med Chem. 2011 May 6;54(11):3926–3934. doi: 10.1021/jm2002487

Table 1.

Inhibition of [³⁵S]-TBPS Binding by Steroids 1, 2 and Structural Analogues^a

Compound	IC₅₀ (nM)	n_Hill
1^b	226 ± 24	1.10 ± 0.11
2^b	2,220 ± 260	1.24 ± 0.14
3^b	190 ± 18	1.14 ± 0.11
4^b	361 ± 58	1.00 ± 0.14
5a	997 ± 187	1.50 ± 0.36
5b	770 ± 98	0.97 ± 0.10
5c	1,020 ± 204	0.94 ± 0.14
6a	128 ± 11	1.44 ± 0.15
6b	2,030 ± 810	0.90 ± 0.23
6c	629 ± 89	1.48 ± 0.25
6d	1,840 ± 480	1.46 ± 0.42

Results presented are from duplicate experiments performed in triplicate. Error limits are calculated as standard error of the mean. Methods were as reported previously.²⁵

These values are from the literature.²¹