Fig. 1. Invasion of ATRA-treated SH-SY5Y cells and effects of cystamine on invasion of ATRA-treated SH-SY5Y cells. (A) Effects of ATRA on invasion of SH-SY5Y cells. The SH-SY5Y cells were treated with various amount of ATRA (1-10 μM). Average number of invaded cell from (B). (B) Photographs of invaded SH-SY5Y cells. Cells invaded through the membrane after 48 h of incubation were stained and photographed. (C) Effects of cystamine on invasion of SH-SY5Y cells. The SH-SY5Y cells were treated with (5 μM) or without ATRA for 24 h or treated with ATRA and various amounts of cystamine for 1 h. Average number of invaded cells from (D). (D) Photographs of invaded SH-SY5Y cells. Cells invaded through the membrane after 48 h of incubation were stained and photographed. *p<0.05 versus control (Con) or #p<0.05 versus ATRA (5 μM).
