Fig. 1. Effect of TNF-α or/and IFN-γ on P-gp mRNA expression in HBMEC cells. Real time reverse transcription polymerase chain reaction (RT-PCR) analysis of P-gp mRNA expression in iHBMEC and pHBMEC without and with pre-treatment with two different concentration of TNF-α, IFN-γ or both cytokines together (10 ng/ml) for 24 hr or 48 hr. *p<0.05; significantly different from 0 ng/ml treatment.
