Fig. 4. Inhibitory effect of two ME products on Ab accumulation in the Tg2576 mice brains. Aβ accumulation in the brain was determined using immunohistochemical analysis by Aβ1-42 specific antibody. Elevated accumulation of extracellular Aβ1-42 was observed by immunohistochemical method as described in the materials and methods (A). Arrow indicated the accumulation of Aβ1-42. The effect of two ME products on Aβ1-42 level in the brain was measured by ELISA kit (B). Values are presented as mean ± S.E.M. from 5 mice. #Significant difference from non-treated Tg2576 mice (p<0.05). BL-ME: Ethanol extract of Magnolia officinalis from Bioland LTD, HFN-ME: Extract product of Magnolia officinalis from Health Freedom Nutrition LLC.
