Table 1.
Characteristics of healthy control subjects and patients with ST elevation myocardial infarction and Tako-Tsubo cardiomyopathy.
| Healthy control subject | ST elevation myocardial infarction | Tako-Tsubo cardiomyopathy | P value | |
|---|---|---|---|---|
| n = 14 | n = 14 | n = 14 | ||
| Age (years) | 62 ± 6 | 70 ± 14 | 64 ± 11 | 0.12 |
| Female (n (%)) | 5 (35) | 12 (86) | 12 (86) | 0.48 |
| Body mass index (kg/m2) | 26.1 ± 0.9 | 26.4 ± 5.1 | 24.3 ± 4.5 | 0.4 |
| LVEF (%) | 66 ± 2 | 47 ± 2 | 42 ± 3 | <0.0001 |
| Cardiovascular risk factors (n (%)) | ||||
| Current smoking | 2 (14) | 3 (21) | 2 (14) | 0.99 |
| Previous smoking | 4 (28) | 1 (7) | 6 (43) | 0.10 |
| Hypertension | 3 (21) | 11 (79) | 7 (50) | 0.01 |
| Diabetes | 1 (7) | 3 (21) | 1 (7) | 0.59 |
| Hyperlipidemia | 4 (28) | 8 (57) | 6 (43) | 0.27 |
| Obesity | 0 | 6 (43) | 5 (36) | 0.02 |
| Creatinine clearance (mL/min) | 96 ± 6 | 77 ± 22 | 104 ± 32 | 0.02 |
| Psychiatric diagnosis (n (%)) | ||||
| Current or past major depressive disorder | 4 (28) | 3 (21) | 10 (71) | 0.02 |
| Generalized anxiety disorder | 0 | 0 | 6 (43) | 0.001 |
| Biological samples | ||||
| Troponin peak (ng/mL) | NA | 124 ± 125 | 3 ± 3 | 0.002 |
| Hemoglobin (g/dL) | 14.3 ± 0.3 | 12.3 ± 1.3 | 12.0 ± 3.8 | 0.001 |
| Platelets counts (1000/mL) | 210 ± 10 | 251 ± 79 | 262 ± 106 | <0.0001 |
Proportions are tested by Fisher's exact test or χ 2 test as appropriate (effective ≤5 or >5, resp.), and quantitative values are tested by analysis of variance (ANOVA test).
LVEF: Left ventricular ejection fraction.