Changes in expression of NMDA receptor subunits of DBA/2J mice at various ages. (a) Representative immunoblots showing the changes of NR1, NR2A, p-NR2AS1232, NR2B levels in DBA/2J and C57BL/6 mice at ages of 3, 6, 9, and 12 months. (b)–(e) Bar chart showing the average densitometric quantification of immunoreactive bands of NR1 (b), NR2A (c), p-NR2AS1232/NR2A (d), and NR2B (e) in DBA/2J and C57BL/6 mice at ages of 3, 6, 9, and 12 months, respectively. *P < 0.05, **P < 0.01 and ***P < 0.001 versus 3-month-old C57BL/6 mice; ##
P < 0.01 and ###
P < 0.001 versus 3-month-old DBA/2J; &&&
P < 0.001 versus age-matched C57BL/6 mice.