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. Author manuscript; available in PMC: 2013 Oct 10.
Published in final edited form as: Nat Commun. 2012;3:1122. doi: 10.1038/ncomms2128

Figure 1. Extracellular Matrix Microarray Platform Presents Combinations of ECM Molecules for Cell Attachment.

Figure 1

(a) ECM microarrays are generated by spotting nearly 800 unique combinations of ECM molecules on glass slides coated with polyacrylamide followed by seeding of cells onto the slides. (b) Polyacrylamide acts to entrap molecules of a large range of molecular weights. (c) Verification of presentation of all molecules by immunolabeling (colored spots) or NHS-fluorescein labeling (grayscale spots) of all molecules subsequent to array generation and rehydration. (d) Representative images of cells adhered to ECM spots demonstrating selective adhesion in the locations of ECM. Scale bar on five-spot image is 200µm. Scale bars on single-spot images are 50µm.