Table 1.
Mechanism | Drug |
---|---|
Blockage of voltage-gated sodium channels | Phenytoin |
Fosphenytoin | |
Carbamazepine | |
Valproate | |
Lamotrigine | |
Oxcarbazepine | |
| |
Enhancement of GABA inhibition | Phenobarbital |
Primidone | |
Diazepam | |
Lorazepam | |
Clonazepam | |
Tiagabine | |
Valproate | |
| |
Blockage of low-threshold (T-type) Ca2+ channels | Ethosuximide |
Gabapentin | |
Valproate | |
| |
Reduction of glutamate excitation | Felbamate |
Gabapentin | |
Parampanel |