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. 2013 Sep 17;14(9):19086–19108. doi: 10.3390/ijms140919086

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Arterial plaque coverage. (a) Atherosclerotic plaque coverage in Sudan III-stained luminal sections of thoracic arteries harvested from four groups of rabbits (n = 4 per group), administered normal feed (control) or feed supplemented with 2% cholesterol (HC, high cholesterol). Plaque coverage evaluated following a 12-week (short) or 40-week (long) time-course is shown as the average percentage of plaque coverage in arteries from each group of animals ± SEM; (b) The extent of atherosclerosis in arterial lumens is represented in histogram form as percentage plaque coverage; and as photographic images of representative arterial sections shown in the same frames as each histogram. *p < 0.05 for comparison of percentage atherosclerotic plaque coverage in arteries of non-hypercholesterolemic long (control long) rabbits versus hypercholesterolemic long (HC long) and hypercholesterolemic short (HC short) rabbits. # p < 0.05 for comparison of percentage atherosclerotic plaque coverage in arteries of hypercholesterolemic long (HC long) rabbits versus hypercholesterolemic short (HC short) rabbits.