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. 2013 Sep 23;14(9):19276–19293. doi: 10.3390/ijms140919276

Figure 5.

Figure 5

Schematic illustration of the proposed osteogenic differentiation of hMSCs induced by magneto-mechanical stimulation combined with biochemical signals. MNPs were functionalized with RGD peptide or PDGFRα antibody to target either integrin ανβ3 or PDGFRα on cell surface membrane of hMSCs. When exposed to MFB, induced mechano-transduction coupled with biochemical signals directed the osteogenic differentiation and mineralization of hMSCs.