Table 1.
The results of FTIR spectroscopy analyses, giving a comparison of the mineralization in magnetically stimulated [platelet-derived growth factor receptor α (PDGFRα) and RGD treatment] and non-treated (Cell) human bone marrow-derived mesenchymal stem cells (hMSCs) following 3 weeks of culture (n = 3, mean ± SD). Mineral crystallinity is a parameter that corresponds to the crystallite size and perfection, and was calculated from the intensity ratios of sub-bands at 1030 (stoichiometric apatite) and 1020 cm−1 (nonstoichiometric apatite) [33]. Collagen cross-link ratio (XLR) is a parameter reflecting the relative ratio of nonreducible and reducible collagen cross-links, expressed as the absorbance ratio at two specific wavenumbers (1660 and 1690 cm−1) [34].
| Group | Mineral/matrix ratio | 1660/1690 ratio | 1020/1030 ratio |
|---|---|---|---|
| PDGFRα treatment | 3.56 ± 0.52 | 2.48 ± 0.02 | 1.08 ± 0.01 |
| RGD treatment | 2.82 ± 0.56 | 2.45 ± 0.08 | 0.07 ± 0.01 |
| Cell (nontreated) | 2.53 ± 0.44 | 2.55 ± 0.04 | 1.06 ± 0.06 |