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. 2013 Oct 10;9(10):e1003807. doi: 10.1371/journal.pgen.1003807

Figure 7. Infarct volume is increased in Itgal knockout (KO) mice.

Figure 7

A. Collateral number does not differ between B6 and Itgal KO mice. B. The posterior faces of representative 1-mm coronal sections from B6 and Itgal KO mice are shown. The size of the infarct in Itgal KO is larger than B6 mice. C. Itgal KO mice on the B6 background exhibit infarct volume ∼3-fold larger than that of B6 mice (15.9 vs. 4.7 mm3). ** P<0.001. D. Increased neuronal death in the cortical region of the brain slices from Itgal KO mice compared to control B6 mice 24 hr after 5.5 min OGD. E. Deficiency of Itgal increases neuronal cell death by ∼50% compared to B6 mice. Values represent mean ± SEM from at least 5 animals per group. ** P<0.001.