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. 2013 Oct 10;8(10):e75917. doi: 10.1371/journal.pone.0075917

Figure 3. GCN2 regulation of liver and serum triglycerides and expression of PPARγ2 and lipid droplet proteins FSP27 and CIDEA in the liver is dependent upon dietary fat.

Figure 3

(A). Liver triglyceride (TG) content of mice of indicated genotypes after Low Fat Chow (LFC) and Medium Fat Chow (MFC) feeding (mean ± SEM, n = 8, *p<0.05 Gcn2 KO vs. WT). (B). Serum triglyceride (TG) level of mice of indicated genotypes after LFC and MFC feeding (mean ± SEM, n = 8, *p<0.05 Gcn2 KO vs. WT). (C). Expression of Pparγ1, Pparγ2, Fsp27, Cidea, Plin1, Plin2 and Sgms2 mRNAs in livers of mice of indicated genotypes fed with LFC and MFC (normalized to wildtype mice on LFC, mean ± SEM, n = 4, *p<0.05 Gcn2 KO vs. WT).