Table 4. Principal perinatal outcomes by level of proteinuria adjusted for age and ethnicity with risk ratios in comparison with PE 300 group (proteinuria 300- 499 mg/24 hours).
Preeclampsia | Preeclampsia | Chronic Hypertension | Gestational Hypertension | |
---|---|---|---|---|
300-499 mg/day | ≥500 mg/day | |||
N | 60 | 161 | 615 | 110 |
SGA (<10th adjusted centile), N (%) | 24 (40.0%) | 84 (52.5%) | 122 (20.1%) | 28 (25.7%) |
Risk ratio | 1.30 (0.93 to 1.82) | 0.49 (0.35 to 0.69)*** | 0.63 (0.40 to 0.97)* | |
SGA (<5th adjusted centile), N (%) | 19 (31.7%) | 79 (49.4%) | 81 (13.3%) | 18 (16.5%) |
Risk ratio | 1.56 (1.04 to 2.33)* | 0.48 (0.32 to 0.72)*** | 0.48 (0.32 to 0.72)* | |
Total deaths, N (%) | 2 (3.3%) | 4 (2.5%) | 21 (3.4%) | 0 (0.0%) |
Preterm delivery (<37w), N (%) | 15 (25.0%) | 99 (61.5 %) | 83 (13.5%) | 10 (9.1%) |
Risk ratio | 2.41 (1.56 to 3.89)*** | 0.60 (0.38 to 0.95)* | 0.51 (0.23 to1.10) | |
Spontaneous preterm delivery, N (%) | 2 (3.3%) | 4 (2.5%) | 32 (5.2%) | 4 (3.6%) |
Iatrogenic preterm delivery, N (%) | 13 (21.7%) | 95 (59.0%) | 51 (8.3%) | 6 (5.5%) |
Risk ratio | 2.72 (1.66 to 4.48)*** | 0.41 (0.24 to 0.71)*** | ||
Preterm delivery < 34 weeks, N (%) | 8 (13.3%) | 43 (26.7%) | 41 (6.7%) | 0 (0.0%) |
Risk ratio | 1.97 (1.01 to 3.85)* | 0.64 (0.32 to 1.28) | ||
Surfactant use, N (%) | 2 (3.3%) | 21 (13.0%) | 15 (2.4%) | 0 (0.0%) |
Mechanical Ventilation, N (%) | 4 (6.7%) | 20 (12.4%) | 15 (2.4%) | 1 (0.9%) |
Respiratory distress syndrome, N (%) | 5 (8.3%) | 30 (18.6%) | 18 (2.9%) | 0 (0.0%) |
Risk ratio: comparison with preeclampsia with proteinuria of 300–499 mg/24 hours; *P≤0.05; **P≤0.01; ***P≤0.001