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. 2013 Oct 10;8(10):e76083. doi: 10.1371/journal.pone.0076083

Table 4. Principal perinatal outcomes by level of proteinuria adjusted for age and ethnicity with risk ratios in comparison with PE 300 group (proteinuria 300- 499 mg/24 hours).

Preeclampsia Preeclampsia Chronic Hypertension Gestational Hypertension
300-499 mg/day ≥500 mg/day
N 60 161 615 110
SGA (<10th adjusted centile), N (%) 24 (40.0%) 84 (52.5%) 122 (20.1%) 28 (25.7%)
Risk ratio 1.30 (0.93 to 1.82) 0.49 (0.35 to 0.69)*** 0.63 (0.40 to 0.97)*
SGA (<5th adjusted centile), N (%) 19 (31.7%) 79 (49.4%) 81 (13.3%) 18 (16.5%)
Risk ratio 1.56 (1.04 to 2.33)* 0.48 (0.32 to 0.72)*** 0.48 (0.32 to 0.72)*
Total deaths, N (%) 2 (3.3%) 4 (2.5%) 21 (3.4%) 0 (0.0%)
Preterm delivery (<37w), N (%) 15 (25.0%) 99 (61.5 %) 83 (13.5%) 10 (9.1%)
Risk ratio 2.41 (1.56 to 3.89)*** 0.60 (0.38 to 0.95)* 0.51 (0.23 to1.10)
Spontaneous preterm delivery, N (%) 2 (3.3%) 4 (2.5%) 32 (5.2%) 4 (3.6%)
Iatrogenic preterm delivery, N (%) 13 (21.7%) 95 (59.0%) 51 (8.3%) 6 (5.5%)
Risk ratio 2.72 (1.66 to 4.48)*** 0.41 (0.24 to 0.71)***
Preterm delivery < 34 weeks, N (%) 8 (13.3%) 43 (26.7%) 41 (6.7%) 0 (0.0%)
Risk ratio 1.97 (1.01 to 3.85)* 0.64 (0.32 to 1.28)
Surfactant use, N (%) 2 (3.3%) 21 (13.0%) 15 (2.4%) 0 (0.0%)
Mechanical Ventilation, N (%) 4 (6.7%) 20 (12.4%) 15 (2.4%) 1 (0.9%)
Respiratory distress syndrome, N (%) 5 (8.3%) 30 (18.6%) 18 (2.9%) 0 (0.0%)

Risk ratio: comparison with preeclampsia with proteinuria of 300–499 mg/24 hours; *P≤0.05; **P≤0.01; ***P≤0.001