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. 2013 Oct 10;8(10):e75602. doi: 10.1371/journal.pone.0075602

Table 1. Clinical characteristics of patients with PiB(-) and PiB(+) SVaD.

PiB(-) (n = 45) PiB(+) (n = 23) p
Demographics
Age 71.9±7.4 78.1±4.7 <0.001
Gender, M:F 21:24 06:17 0.101
Education 8.3±4.8 9.1±5.5 0.523
Risk factors
Hypertention 36 (80%) 18 (78.3%) 1.000
Diabetes 11 (24.4%) 6 (26.1%) 0.882
Hyperlipidemia 20 (44.4%) 6 (26.1%) 0.141
Cognition
MMSE 21.4±4.7 18.7±4.9 0.036
CDR-SOB 6.0±3.8 6.5±3.8 0.61
MRI markers
WMH volume, ml 41.9±15.6 45.5±22.9 0.447
Total lacune, n 21.1±18.3 7.0±6.9 <0.001
Intracranial volume 1381.4±134.3 1390.4±155.1 0.804
APOE genotype
APOE4 carriers 9 (21.4%) 10 (43.5%) 0.062
Medication
Antipsychotics 1 (2.2%) 2 (8.7%) 0.219
Antidepressant 5 (11.1%) 2 (8.7%) 0.756
Anxiolytics 4 (8.9%) 4 (17.4%) 0.303

Abbreviations: PiB, Pittsburgh compound B; MMSE, Mini-Mental State Examination; CDR-SOB, clinical dementia rating sum of boxes; WMH, white matter hyperintensities; APOE4, Apolipoprotein E epsiolon 4.