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. 2013 Oct 10;8(10):e77070. doi: 10.1371/journal.pone.0077070

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© 2013 Endo et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

A, HOTAIR expression levels of cancerous and adjacent noncancerous tissues from the gastric cancer patients were examined by qRT-PCR and normalized by the GAPDH expression level. The expression levels of HOTAIR were significantly higher in carcinoma lesions compared to those of non-cancerous lesions (P= 0.019). B and C, The human gastric cancer tissues were further classified according to the HOTAIR expression level into a High-HOTAIR group (HOTAIR / GAPDH >1.0) and Low-HOTAIR group (HOTAIR /GAPDH < 1.0) in the intestinal (B) and diffuse type (C) of gastric cancer, respectively.