Table 2. Immunologic and Virologic responses to ART.
BL | Wk 4 | Wk 8 | Wk 12 | Wk 24 | Wk 48 | Wk 96 | |
---|---|---|---|---|---|---|---|
Number of Subjects (n) | 50 | 50 | 50 | 50 | 50 | 50 | 49 |
Median (IQR) CD4 count (cells/µL) | 186 (113-263) | 240 (176–330) | 289 (210–394) | 289 (187–374) | 291 (216-414) | 333 (247-474) | 338 (275-505) |
Median (IQR) change in CD4 count from BL (cells/µL) | 64 (31-96) | 109 (63-153) | 107 (59-148) | 114 (56-185) | 142 (91-254) | 180 (113-281) | |
Median (IQR) HIV-VL (log10copies/ml) | 4.9 (4.3-5.3) | 2.6 (2.1-2.8) | 2.0 (1.6-2.3) | 1.6 (1.6-2.1) | 1.6 (1.6-1.6) | 1.6 (1.6-1.6) | 1.6 (1.6-1.6) |
Subjects with HIV-VL <40 copies/ml (n) | 0 | 3 | 15 | 25 | 44 | 44 | 44 |
Positive CMV-Sp-CD4 T cell response (n) | 40 | 49 | 50 | 49 | 48 | 48 | 48 |