Table 3. Factors associated with the frequency of naïve CD4 T cells.
Univariate Analysis |
Multivariate Analysis |
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---|---|---|---|---|
Factors | Change co-efficient (95% CI) in naïve CD4 (% of CD4 cells) | P value | Change co-efficient (95% CI) in naïve CD4 (% of CD4 cells) | P value |
CD4 count at wk 96 (per 50 cells/µL) | 2.2 (1.3 - 3.1) | <0.001 | 2.2 (1.5 - 3.0) | <0.001 |
CMV-Sp-CD4 at wk 96 (% of CD4 T cells) | -5.4 (-8.5 - -2.3) | 0.001 | -5.4 (-7.8 - -3.1) | 0.001 |
Age (yrs) | -0.9 (-1.4 - -0.4) | 0.001 | ||
Gender | ||||
Male | 5.3 (-4.9 - 15.4) | 0.302 | ||
Female | ref | |||
Mode of HIV acquistion | ||||
MSM | 6.9 (-2.1 - 15.9) | 0.128 | ||
Others | ref | |||
CDC category | ||||
CDC A and B | ref | |||
CDC C | -11.0 (-22.4 - 0.3) | 0.057 | ||
TB infection | ||||
Present | -2.5 (-11.9 - 6.8) | 0.589 | ||
Absent | ref | |||
Smoking | ||||
Current smoker | -2.3 (-12.9 - 8.4) | 0.672 | ||
Non smoker | ref |