Skip to main content
. 2013 Oct 10;8(10):e77493. doi: 10.1371/journal.pone.0077493

Figure 2. CCR2 deficiency suppresses the accumulation of bone marrow-derived fibroblasts in the kidneys after UUO.

Figure 2

A. Representative photomicrographs of kidney sections from WT and CCR2-KO mice 1 week after UUO stained for CD45 (red), PDGFR-β (green), and DAPI (blue). B. Quantitative analysis of CD45+ and PDGFR-β+ fibroblasts in the kidneys of WT and CCR2-KO mice 1 week after UUO. ** P < 0.01 vs WT controls, # P < 0.05 vs WT-UUO, and + P < 0.05 vs KO-UUO. n=6 per group. C. Representative photomicrographs of kidney sections from WT and CCR2-KO mice 1 week after UUO stained for CD45 (red), procollagen I (green), and DAPI (blue). D. Quantitative analysis of CD45+ and procollagen I+ fibroblasts in the kidneys of WT and CCR2-KO mice 1 week after UUO. ** P < 0.01 vs WT controls, # P < 0.05 vs WT-UUO, and + P < 0.05 vs KO-UUO. n=6 per group.