Figure 5. CCR2 deficiency suppresses renal fibrosis and extracellular matrix deposition in the kidney.

A. Representative photomicrographs show kidney sections stained with picrosirius red for assessment of total collagen deposition. B. Bar graph shows quantitative analysis of renal interstitial collagen in different groups as indicated. ** P < 0.01 vs WT controls, + P < 0.05 vs KO UUO, and # P < 0.05 vs WT UUO. n= 6 per group.