Figure 7. CCR2 deficiency reduces fibronectin expression in the kidney.
A. Representative photomicrographs of fibronectin immunostaining in the kidneys of WT and CCR2-KO mice at day 14 after UUO (original magnification X400). B. Quantitative analysis of interstitial fibronectin protein expression in the kidney sections of WT and CCR2-KO mice. ** P < 0.01 vs WT controls, # P < 0.05 vs WT UUO, and + P < 0.05 vs KO UUO. n=6 per group. C. Representative Western blots show the protein levels of fibronectin in the kidneys of WT and CCR2-KO mice. D. Quantitative analysis of fibronectin protein expression in the kidneys of WT and CCR2-KO mice. ** P < 0.01 vs WT controls, # P < 0.05 vs WT UUO, and + P < 0.05 vs KO UUO. n=5 per group.