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. 2013 Oct 10;8(10):e77268. doi: 10.1371/journal.pone.0077268

Table 3. Multivariate analysis to estimate the risk of ATV/r- over DRV/r-containing antiretroviral therapies for nephrolithiasis.

Model 1 crude (n=1,057)
Model 2 adjusted (n=1,056)
Model 3 adjusted (n=1,021)
HR 95%CI HR 95%CI HR 95%CI
ATV/r use over DRV/r 27.05 3.687-198.5 27.08 3.680-199.3 21.47 2.879-160.2
Age per 1 year 1.009 0.980-1.039 1.006 0.976-1.037
Male sex 1.939 0.441-8.528 1.202 0.262-5.512
Weight per 1 kg increment 0.988 0.956-1.021 0.979 0.947-1.012
Tenofovir use 0.678 0.313-1.470
Baseline serum uric acid per 1mg/dl increment 1.418 1.150-1.750
Past history of renal stone 1.661 0.520-5.307
Past exposure to IDV 0.491 0.100-2.403

HR, Hazard ratio; CI, confidence interval; ATV/r, ritonavir-boosted atazanavir; DRV/r, ritonavir-boosted darunavir; HIV, IDV, indinavir.

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