Table 6. Factors influencing caregivers HRQOL and family function of children with FC.

Factors	Score of FIM scale
	Physical	Emotional	Social	Cognitive	Communication	Worry	Daily Activities	Relationships	Summary
Age (year)	—	—	-0.31	—	-0.23	-0.39	-0.25	—	-0.36
Caregiver education level
9–12 years	0.29	0.30	0.33	0.29	0.35	0.32	0.21	0.30	0.44
≥ 13 years	0.72	0.56	0.24	0.47	0.32	0.48	0.49	0.28	0.42
Child’s HRQOL	0.22	0.23	0.33	0.21	0.34	-0.21	0.43	0.54	0.69
Family economic status	—	0.26	0.15	—	—	—	0.37	—	0.26
Duration of constipation(months)	-0.19	-0.26	-0.24	-0.27	-0.23	0.28	-0.24	-0.28	-0.28
Frequency of defecation(times/week)	0.24	0.35	0.33	0.41	0.72	-0.31	0.49	—	1.02
Painful defecation occurrence	-1.09	-1.16	-1.24	-0.97	-1.23	1.09	-0.86	-0.98	-1.41
Non-specific abdominal pain	-0.79	-1.16	-0.64	-0.47	-0.53	0.99	-0.68	-0.39	-1.19
Determination coefficient R 2	0.66	0.36	0.47	0.28	0.51	0.76	0.46	0.44	0.64

Notes: (1) Multiple step-wise regression analysis was used to select factors that influenced HRQOL of caregivers and their family function, with scores of each subscale and summary scale as dependent variables, and with age (years), gender, caregiver education level, child-caregiver relationship, family economic status, duration of constipation (months), frequency of defecation (times/week), painful defecation, non-specific abdominal pain and HRQOL score of child as independent variables (2). The data listed in Table 6 were standardized partial regression coefficient and the “— ” symbol indicates that this factor cannot enter the regression model. All standardized partial regression coefficients listed in the table were statistically significant (p<0.05) (3). Child’s HRQOL was the summary score of PedsQL^TM 4.0 Generic Core Scale.