Table 10.

Summary of studies on resveratrol for the treatment of spinal muscular atrophy.

Study	Country	Study type	Results	Disadvantage
Sakla and Lorson (2008)	USA	In vitro (cell-based)	Resveratrol elevated SMN2-luciferase expression by six fold and increased the exon 7-inclusion by 1.4 fold in a luciferase assay. These effects translated into only a one-fold increase in the full-length SMN2 transcript level.	Not reported
Dayangac-Erden et al. (2009)	Turkey	In vitro (cell-based)	Resveratrol increased the full-length SMN2 mRNA and protein levels by 1.3-fold.	Not reported