Table 2.
Genes with high mutation frequency in lung cancer (n = 145).
| Gene symbol | Gene symbol | Gene symbol | Gene symbol | Gene symbol |
|---|---|---|---|---|
| EVI1 | EPHA3 | CBL | MAP2K4 | PDIA4 |
| HYRC | UBR5 | RUNX1T1_ENST00000265814 | ITPR1 | PAK6 |
| EGFR | PIK3CG | RUNX1T1 | FLT4 | P2RY8 |
| KRAS | PDGFRA | RET | FLT3 | NRG3 |
| TP53 | KDR | PPP1R3A | BRCA2 | MECOM |
| CDKN2A | ALK | NTRK1 | ABL2 | LMTK3 |
| STK11 | TTN | MEN1 | USP29 | LATS1 |
| BRAF | PKHD1 | KSR2 | RNF213 | KIAA1804 |
| PIK3CA | LPHN3 | HRAS | PTPN11 | JAK3 |
| RB1 | GRM8 | FGFR4 | PTCH2 | JAK2 |
| ERBB2 | PTPRD | ROS1 | PTCH1 | ITPR3 |
| PTEN | FBXW7 | ROR2 | PAK3 | IRS1 |
| NFE2L2 | KEAP1 | PIK3C3 | NPY5R | IRAK2 |
| MET | ITK | PIK3C2G | NCOA2 | INHBA |
| CTNNB1 | SMAD4 | NOTCH4 | MTOR | HERC1 |
| CDKN2a(p14) | PAK7 | NOTCH3 | MKRN3 | HEPH |
| NRAS | NTRK2 | NLRP3 | MERTK | FBXO10 |
| MUC16 | KIT | MYO3B | LTK | ERCC6 |
| NF1 | INSRR | LMTK2 | HECW1 | EPHB3 |
| BAI3 | GLI3 | GRM1 | FLT4_ENST00000261937 | EPHA4 |
| SMARCA4 | FGFR2 | EPHB6 | DOCK3_ENST00000266037 | DNER |
| MUC16_ENST00000331986 | CSMD3 | EPHA7 | CREBBP | DGKB |
| ATM | TLR4 | ENSG00000121031 | CDC42BPA | CCKBR |
| NTRK3 | PRKDC | TLN1 | AKT1 | BAI2 |
| ERBB4 | NOTCH2 | TERT | ZMYM2_ENST00000456228 | APLNR |
| EPHA5 | FLT1 | TBX22 | VEGFC | ANKK1 |
| APC | FBXW7_NM_018315_2 | TAF1L | TYK2 | AKAP9_ENST00000356239 |
| NOTCH1 | EPHB1 | MSH6 | ROBO2 | AKAP9 |
| LRP1B | CDH11 | MLL | RBL1 | ADAMTSL3 |