Table 3.
Mutation events for EGFR mutation kits.
| Mutation in EGFR | Mutation frequency |
|---|---|
| L858R | 2688 |
| c.2573T > G:L858R | 1378 |
| E746_A750del | 955 |
| c.2235_2249del15:E746_A750del | 609 |
| T790M | 346 |
| c.2236_2250del15:E746_A750del | 326 |
| c.2240_2257del18:L747_P753 > S | 113 |
| c.2369C > T:T790M | 102 |
| L747_P753 > S | 81 |
| c.2239_2248TTAAGAGAAG > C:L747_A750 > P | 72 |
| L861Q | 70 |
| L747_T751del | 58 |
| c.2237_2255 > T:E746_S752 > V | 47 |
| L747_A750 > P | 47 |
| G719S | 45 |
| c.2240_2254del15:L747_T751del | 43 |
| c.2582T > A:L861Q | 39 |
| G719A | 36 |
| L747_S752del | 36 |
| S768I | 34 |
| c.2239_2256del18:L747_S752del | 31 |
| c.2155G > A:G719S | 24 |
| c.2156G > C:G719A | 24 |
| L747_P753del | 24 |
| E746_S752 > V | 23 |
| c.2155G > T:G719C | 20 |
| c.2239_2253del15:L747_T751del | 20 |
| E746_T751del | 20 |
| c.2239_2251 > C:L747_T751 > P | 19 |
| c.2303G > T:S768I | 19 |
| c.2237_2251del15:E746_T751 > A | 18 |
| G719? | 16 |
| c.2239_2247del9:L747_E749del | 15 |
| c.2497T > G:L833V | 15 |
| G719C | 14 |
| L747_A750del | 13 |
| L747_T751 > P | 13 |
| c.2125G > A:E709K | 12 |
| D770_N771insSVD | 12 |
| L747_P753 > Q | 12 |
| E746_T751 > A | 11 |
| P772_H773insPR | 11 |
| c.2126A > C:E709A | 10 |
| H773R | 7 |
| R776H | 7 |
| c.2233_2247del15:K745_E749del | 6 |
| c.2238_2252del15:L747_T751del | 6 |
| c.2254_2277del24:S752_I759del | 6 |
| c.2582T > G:L861R | 6 |
| H773_V774insNPH | 6 |
| L833V | 6 |
| c.2126A > G:E709G | 5 |
| c.2237_2253 > TTGCT:E746_T751 > VA | 5 |
| c.2237_2256 > TT:E746_S752 > V | 5 |
| c.2253_2276del24:S752_I759del | 5 |
| c.2311_2312ins9:D770_N771insSVD | 5 |
| c.2319_2320ins9:H773_V774insNPH | 5 |
| c.2504A > T:H835L | 5 |
| c.2543C > T:P848L | 5 |
| c.89_889del801:V30_R297 > G | 5 |
| K745_A750del | 5 |
| L747_T751 > S | 5 |
| L747P | 5 |
| L861R | 5 |
| V843I | 5 |