Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Oct 11;7:179. doi: 10.3389/fncel.2013.00179

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © Bouzier-Sore and Pellerin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Main metabolic pathways implicated in energy production in astrocytes with a prominent role for glycolysis. In order to regenerate cytosolic NAD⁺ levels and maintain glycolytic rate, astrocytes have two options: transfer cytosolic NADH in mitochondria through specific mitochondrial NADH shuttles or convert pyruvate into lactate in the cytosol. AcCoA, acetylCoenzyme A; HK, hexokinase; LDH, lactate dehydrogenase; PDH, pyruvate dehydrogenase; PFK1, phosphofructokinase 1; PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; PPP, pentose phosphate pathway; RC, respiratory chain; TCA, tricarboxylic acid cycle.

HHS Vulnerability Disclosure