Table 1.

Animal Characteristics and Organ Weights of Preterm and Term Neonatal Guinea Pigs.^a

	n	Litters	GA Delivery	Birth Weight	PM Weight	Brain Weight	Liver Weight	BLR
Term	22	11	68.2 ± 0.16b	87.3 ± 2.50b	83.3 ± 2.58b	2.3 ± 0.03	3.6 ± 0.15	0.66 ± 0.02
Female	10	8	68.3 ± 0.21b	86.3 ± 3.32b	82.9 ± 3.37b	2.3 ± 0.03	3.5 ± 0.16	0.67 ± 0.03
Male	12	9	68.2 ± 0.24b	88.2 ± 3.76b	83.7 ± 3.95b	2.3 ± 0.04	3.7 ± 0.24a	0.65 ± 0.04
Preterm	20	19	62.5 ± 0.15	69.0 ± 1.92	64.1 ± 1.70	2.1 ± 0.03	3.0 ± 0.11	0.72 ± 0.02
Female	10	9	62.4 ± 0.22	67.3 ± 2.88	62.3 ± 2.52	2.1 ± 0.04	2.9 ± 0.13	0.72 ± 0.03
Male	10	10	62.6 ± 0.22	70.7 ± 2.58	66.0 ± 2.26	2.2 ± 0.03	3.1 ± 0.03ab	0.73 ± 0.04
Preterm Prog	16	15	62.6 ± 0.16	67.1 ± 2.06	63.2 ± 1.97	2.1 ± 0.04	2.9 ± 0.14	0.73 ± 0.03
Female	8	8	62.7 ± 0.29	69.9 ± 3.59	66.2 ± 3.54	2.1 ± 0.05	3.1 ± 0.26	0.71 ± 0.04
Male	8	7	62.5 ± 0.20	64.3 ± 1.73	60.3 ± 1.24	2.1 ± 0.06	2.8 ± 0.12b	0.76 ± 0.04

Abbreviations: GA delivery, gestational age at delivery; PM, postmortem; BLR, brain-to-liver weight ratio; Prog, progesterone replacement; SEM, standard error of the mean.

^aValues expressed as mean ± SEM; weight (g). Different lower case letters indicate significant difference in male liver weights. Liver weights and BLR exhibited unequal variance by Bartlett test and were transformed by square root for analysis.

^b P < .05 term is significantly different from preterm groups.