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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Clin Neurosci. 2012 Dec 21;20(2):281–286. doi: 10.1016/j.jocn.2012.05.029

Table 2.

Hyam’s grading criteria

Low-grade High-grade
1 2 3 4
Lobular architecture + + ± ±
Mitotic activity − + ++ +++
Nuclear pleomorphism − ± + ++
Rosettes HW± HW± FW± −
Necrosis − − + ++

HW=Homer Wright rosette, FW= Flexner–Wintersteiner rosette. (Reproduced from Morita et al.3 with the kind permission of Wolters Kluwer Health.)