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. Author manuscript; available in PMC: 2013 Oct 11.
Published in final edited form as: Reproduction. 2010 Jul 28;140(4):605–612. doi: 10.1530/REP-10-0263

Figure 3. Concentration-dependent effects of IL-1β and TNF-α on IL-11 output by decidual cell monolayers maintained in E2 + MPA.

Figure 3

Confluent, leukocyte-free first trimester decidual cells were incubated for 7 days in 10−8 M E2 + 10−7 M MPA, then switched to DM with the steroids ± the indicated amount of IL-1β (0.01 to 10.0 ng/ml) or TNF-α (0.01 to 10.0 ng/ml). IL-11 levels were measured by ELISA in conditioned DM and normalized to cell protein. Bars represent mean ± SEM of IL-11 levels as pg/ml/µg cell protein (n=3 separate patients’ decidual specimens, mean ± SEM). * versus E2 + MPA; p<0.05.