Table 4.
Differences between controls and patients with microscopic colitis (MC).
| Controls N = 737 % |
MC N = 131 % | Controls/microscopic colitis | ||
|---|---|---|---|---|
|
| ||||
| Crude OR, 95% CI | OR, 95% CI | |||
| Age at menarche (year) | ||||
| Missing value | 0 | 8.4 | “–” | “–” |
| ≤12 (reference) | 19.1 | 24.4 | 1.00 | 1.00 |
| >12 to <15 | 54.3 | 48.9 | 0.70 (0.44–1.12) | 0.65 (0.38–1.09) |
| ≥15 | 26.1 | 18.3 | 0.55 (0.31–0.98) | 0.48 (0.26–0.91) |
| Parity | ||||
| Missing value | 2.6 | 3.1 | “–” | “–” |
| Nullipara (reference) | 11.4 | 9.2 | 1.00 | 1.00 |
| Parous | 86.0 | 87.8 | 1.27 (0.67–2.40) | 1.21 (0.61–2.40) |
| Age at first childbirth (year) | ||||
| Missing value | 2.6 | 3.8 | “–” | “–” |
| Nullipara (reference) | 11.1 | 9.2 | 1.00 | 1.00 |
| ≤25 | 53.6 | 61.8 | 1.40 (0.73–2.69) | 1.46 (0.72–2.96) |
| >25 | 32.4 | 25.2 | 0.94 (0.46–1.91) | 0.79 (0.37–1.69) |
| Age at menopause (year) | ||||
| Missing value* | 32.8 | 22.1 | “–” | “–” |
| ≤45 (reference) | 11.0 | 20.6 | 1.00 | 1.00 |
| >45 to <53 | 39.9 | 32.8 | 0.44 (0.26–0.75) | 0.30 (0.16–0.56) |
| ≥53 | 16.0 | 24.4 | 0.81 (0.45–1.46) | 0.53 (0.28–1.03) |
| Exposure to OC | ||||
| Missing value | 0 | 1.5 | “–” | “–” |
| Never (reference) | 50.2 | 23.7 | 1.00 | 1.00 |
| Ever | 49.8 | 74.8 | 3.19 (2.08–4.89) | 7.49 (4.46–12.43) |
| Exposure to HRT | ||||
| Missing value | 0.4 | 0 | “–” | “–” |
| Non (reference) | 79.5 | 91.6 | 1.00 | 1.00 |
| Current | 20.1 | 8.4 | 0.36 (0.19–0.69) | 0.42 (0.22–00.83) |
| Bilateral oophorectomy | ||||
| Missing value | 66.5 | 7.6 | “–” | “–” |
| No (reference) | 29.0 | 76.3 | 1.00 | 1.00 |
| Yes | 4.2 | 16.0 | 1.45 (0.79–2.65) | 1.19 (0.60–2.35) |
Notes:
*
Missing values includes missing values and premenopausal women. Calculations were adjusted for age, smoking habits, alcohol habits, level of education, and employment.
Abbreviations: HRT, hormonal replacement therapy; CI, Confidence interval; OC, oral contraceptives; OR, Odds ratio.