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. 2013 Oct 2;20(Pt 6):974–979. doi: 10.1107/S0909049513020785

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© Takayoshi Kinoshita et al. 2013

This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.

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Overall structure of CK2α at 1.06 Å resolution. (a) A ribbon model. The five alternative conformations were observed in the interior of the molecule (black dashed box). (b) A solvent accessible surface. The N-terminal extension, N-lobe, hinge region, αD-helix and C-lobe are displayed by violet, blue, yellow, orange, light-blue ribbons, respectively. The nicotinic acid and ethylene glycol molecules are shown as ball and stick models. The alternative conformation loci are indicated by the red side chains.