Figure 1. Clinical symptoms in adults by age distribution (18–44 and ≥45 years) at onset.

(A) First symptom (age 18–44 = 338, and age ≥45 = 31). The frequency of memory dysfunction shows a trend: p = 0.075. (B) Cumulative symptoms during the first month of the disease. For each color, the left column refers to patients 18–44 years (n = 333), and the right solid column to patients ≥45 years (n = 31). *p = 0.026.