Table 3. Association of GRM7 SNP rs11928865 in patients with different audiogram patterns of ARHI (based on the K-means cluster analysis) and in control subjects.

Group		Genotype		P for Genotype			Allele		P for Allele	OR for T Allele (95%CI)
	AA	AT	TT	Dominant model	additive model	recessive model	A	T
							minor allele	major allele
Control subjects (n=324 )
Count	11	118	195				140	508
Frequency (%)	3.40%	36.42%	60.19%				21.60%	78.40%
All case patients(n=982)				0.12817	0.00178	0.00051			0.00100	1.482(1.185-1.852)
Count	19	270	693				308	1656
Frequency (%)	1.93%	27.49%	70.57%				15.68%	84.32%
FL subgroup case patients(n=200)				0.05169	0.89450	0.70260			0.66400	0.936(0.694-1.262)
Count	8	75	117				91	309
Frequency (%)	4.00%	37.50%	58.50%				22.75%	77.25%
SL subgroup case patients(n=337)				0.18986	0.00058	0.00013			0.00020	1.722(1.291-2.296)
Count	6	81	250				93	581
Frequency (%)	1.78%	24.04%	74.18%				13.80%	86.20%
AL subgroup case patients(n=354)				0.04518	0.00041	0.00017			0.00013	1.736(1.306-2.307)
Count	4	89	261				97	611
Frequency (%)	1.13%	25.14%	73.73%				13.70%	86.30%
8D subgroup case patients(n=91)				0.24810	0.11195	0.05010			0.04400	1.582(1.009-2.480)
Count	1	25	65				27	155
Frequency (%)	1.10%	27.47%	71.43%				14.84%	85.16%

OR, odds ratio; CI, confidence interval