Figure 3. Blocking KCa3.1 and Kv1.3 differentially affects the proliferation of A-NK and NA-NK cells.
Dose-dependent effects of TRAM-34 (▪; n = 7 donors each analyzed in triplicates), NS6180 (□; n = 3 donors each analyzed in triplicates), ShK-186 (•; n = 7 donors each analyzed in triplicates), and PAP-1 (○; n = 7 donors each analyzed in triplicates) on [3H] thymidine incorporation by NA-NK and A-NK stimulated with PMA and ionomycin alone (A) or in addition to rhIL-2 and rhIL-15 (B). Data represent the mean ± SEM. *p<0.05, **p<0.01, ***p<0.001.