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A. IRP-1 protein expression in cortical and striatal separated brain tissue was significantly decreased in 12-week-old R6/2 mice compared to age-matched wild-type littermate controls. B. To a lesser extent IRP-2 expression was also decreased in HD model tissue from the same mice but did not reach significance in cortical regions. P-values: *<0.05, **< 0.01, n=5.
