Table 5. Functional classification of potential target genes for miRNAs that changed expression levels at 7 d or 30 d after stimulation.
Biological function | Gene name |
---|---|
7d | |
regulation of transcription | BTG2, IKZF1, ELF4, MAFB, RELA, TP53, ELK3, RUNX2, CBFB, NFATC1, DNM2, PA2G4, VEGFA, SMAD5, NFIX |
cell motion | B4GALT1, ARPC1B, TLN1, BDNF, CD44, ITGA5, CTGF, MET, IL6R |
response to wounding | B4GALT1, CD44, ITGA5, CTGF, GSN, RELA, IL6R, ELK3 |
regulation of cell proliferation | B4GALT1, CAV1, CSF1, RELA, TP53, CDK6, IL6R, CDK4, SESN1, BDNF, CDKN1A, BTG2, RUNX2, RHOG, PA2G4, VEGFA, TP53, CDC25A |
cytoskeleton organization | ARPC1B, TLN1, CAV1, TLN2, GSN |
regulation of phosphorylation | CDKN1A, CAV1, CSF1, MET, IL6R |
membrane organization | CAV1, PLSCR3, TP53, ABCA1, DNM2 |
cation homeostasis | CAV1, ATP6V0E1, TP53 |
intracellular signaling | CAV1, RASSF5, CTGF, GSN, MET, TP53, ABCA1, RHOG, NFATC1, VEGFA, SMAD5, COL1A2, SOCS5 |
ion transport | PLP2, CAV1, ATP6V0E1, SLC4A7, NFATC1 |
protein localization | TLN1, CAV1, TLN2, PTTG1IP, TP53, ABCA1 |
regulation of apoptosis | RASSF5, GSN, TP53 |
immune response | IL1RAP, VEGFA, TP53, IL6R |
30 d | |
intracellular signaling | VEGFA, SMAD5, COL1A2, SOCS5, DLL1 |
cell proliferation | PA2G4, VEGFA, TP53, CDC25A |
regulation of transcription | PA2G4, VEGFA, SMAD5, TP53, NFIX |
Immune response | IL1RAP, VEGFA, TP53, IL6R |
regulation of apoptosis | VEGFA, TP53, IL6R |
For gene name abbreviations see Table 4.