Table 2. Gene expression changes in response to infection.

		SAA2		SAA3		SAA4
		Mean	[Range]	Mean	[Range]	Mean	[Range]
A. pleuropneumoniae
Liver	Infected	12.77	[11.55–13.78]	499.53	[368.02–754.22]	8.59	[8.29–8.76]
	Control	1	[0.12–2.21]	1	[0.32–1.08]	1	[0.53–1.93]
Lung	Infected	5.7	[0.70–12.62]	67.25	[13.64–106.12]
	Control	1	[0.51–1.83]	1	[0.54–1.31]
Spleen	Infected	0.71*	[0.61–0.81]	10.37	[6.25–13.49]
	Control	1	[0.92–1.11]	1	[0.39–1.76]
S. aureus
Liver	Infected	16.25	[11.03–23.05]	45.00	[17.11–77.98]	2.14	[1.22–2.82]
	Control	1	[0.40–2.12]	1	[0.34–2.11]	1	[0.78–1.13]
Lung	Infected	1.54	[1.34–1.77]	27.74	[19.94–40.26]
	Control	1	[0.88–1.12]	1	[0.46–1.42]
Spleen	Infected	0.63	[0.52–0.72]	67.40	[33.83–119.43]
	Control	1	[0.31–1.75]	1	[0.72–1.44]

Mean and range of gene expression fold change of SAA2, SAA3, and SAA4 within liver, lung, and spleen tissues of infected pigs (n = 3) compared with control pigs (n = 3; mean gene expression for each isoform set to 1 for each tissue) from the two separate infection experiments. SAA4 was below detection limit in lung and spleen tissue.

^*SAA2 was below detection limit in the spleen of one of the AP-infected pigs, and the mean thus represents only two pigs.