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. 2013 Oct 11;8(10):e75799. doi: 10.1371/journal.pone.0075799

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© 2013 Johnson et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The y-axes indicate the fraction of the total J-factor that is contributed by the middle state (as in Fig. 2, since the with- and without-promoter constructs have different operators, J-factors and not looping probabilities must be compared). That is, when the ratio is unity, indicated by a horizontal black dashed line, only the middle state is observed; when this ratio is zero, again indicated by a horizontal black dashed line, only the bottom state is observed. Closed circles are no-promoter constructs; open circles are with-promoter. E8 and TA data are a subset of those in [35]. Figure S4 in File S1 shows the looping probabilities and J-factors for the two states instead of the relative measures shown here.

Inline graphic — The y-axes indicate the fraction of the total J-factor that is contributed by the middle state (as in Fig. 2, since the with- and without-promoter constructs have different operators, J-factors and not looping probabilities must be compared). That is, when the ratio is unity, indicated by a horizontal black dashed line, only the middle state is observed; when this ratio is zero, again indicated by a horizontal black dashed line, only the bottom state is observed. Closed circles are no-promoter constructs; open circles are with-promoter. E8 and TA data are a subset of those in [35]. Figure S4 in File S1 shows the looping probabilities and J-factors for the two states instead of the relative measures shown here.