Table 2. Association analysis of 11p15.1-11p15.5 region with hypertension susceptibility.
| Marker | Position | χ2 | df | P | Pb | Candidate (bp) |
|---|---|---|---|---|---|---|
| D11S1318 | 2327223 | 27.17 | 8 | 0.00066 | 0.0040 | NLRP6/AVR (278570) |
| D11S1338 | 5987976 | 4.025 | 2 | 0.1337 | 0.8022 | |
| D11S1323 | 6276714 | 2.914 | 3 | 0.4050 | 1.0000 | |
| D11S1346 | 10959374 | 43.74 | 4 | 0.000000007 | 0.00000004 | ADM (10327248) |
| D11S1315 | 12804576 | 1.508 | 4 | 0.8253 | 1.0000 | |
| D11S1310 | 17622865 | 1.755 | 2 | 0.4158 | 1.0000 |
NLRP6,NLR family, pyrin domain containing 6; AVR, angiotensin-vasopressin receptor; ADM, adrenomedullin. df, degrees of freedom; P, nominal P values; P b, P values with the Bonferroni adjustment. Significant results after bonferroni adjustment (P < 0.05) are shown in boldface type. Marker positions on chromosome 11p15.1-11p15.5 region as per NCBI Human Annotation Release 104, GRCh37.p10-Primary Assembly.