Table 3. Description of the tagged SNPs genotyped.
Gene (chr), SNP | A/R | Position | MAF | P (NT) | P (HT) |
---|---|---|---|---|---|
NLRP6/AVR (11) | |||||
rs7948797 | A/G | 269856 | 0.295 | 0.603 | 0.528 |
rs7937440 | A/G | 272199 | 0.417 | 0.601 | 0.636 |
rs11246048 | T/C | 278039 | 0.365 | 0.533 | 0.238 |
rs4758635 | G/T | 283928 | 0.470 | 0.438 | 0.956 |
ADM (11) | |||||
rs4399321 | A/G | 10323478 | 0.280 | 0.239 | 0.148 |
rs4444073 | A/C | 10331664 | 0.344 | 0.988 | 0.572 |
NLRP6, NLR family, pyrin domain containing 6; AVR, angiotensin-vasopressin receptor; ADM, adrenomedullin; A/R, ancestral allele/rare allele; MAF, minor allele frequency; P (NT), Hardy-Weinberg P value in normotensives; P (HT), Hardy-Weinberg P value in hypertensives. SNP locations as per NCBI Human Annotation Release 104, GRCh37.p10-Primary Assembly.