Table 3.
Ipsilateral and contralateral associations with ankle scintigraphic abnormalities.
| Risk of Ankle Bone Scan Abnormalities | |||
|---|---|---|---|
| Predictor | Side of Association | Hazard Ratio (95% CI) |
P value |
| Ankle Symptoms |
Ipsilateral | 2.13 (1.10, 4.12) |
0.03 |
| Ipsilateral (controlled for contralateral predictor) |
2.30 (1.28, 4.13) |
0.005 | |
| Contralateral (controlled for ipsilateral predictor) |
0.89 (0.48, 1.63) |
0.70 | |
| Contralateral | 1.60 (0.83, 3.09) |
0.16 | |
| Knee JSN | Ipsilateral | 1.14 (0.89, 1.46) |
0.30 |
| Ipsilateral (controlled for contralateral predictor) |
1.08 (0.88, 1.34) |
0.45 | |
| Contralateral (controlled for ipsilateral predictor) |
1.41 (1.14, 1.73) |
0.001 | |
| Contralateral | 1.40 (1.12, 1.76) |
0.003 | |
| Knee OST | Ipsilateral | 1.09 (0.99, 1.20) |
0.07 |
| Ipsilateral (controlled for contralateral predictor) |
1.04 (0.95, 1.14) |
0.42 | |
| Contralateral (controlled for ipsilateral predictor) |
1.12 (1.03, 1.22) |
0.006 | |
| Contralateral | 1.14 (1.05, 1.24) |
0.002 | |
| Knee Malalignment |
Ipsilateral | 1.09 (1.02, 1.17) |
0.01 |
| Ipsilateral (controlled for contralateral predictor) |
1.02 (0.91, 1.15) |
0.68 | |
| Contralateral (controlled for ipsilateral predictor) |
1.09 (0.99, 1.21) |
0.08 | |
| Contralateral | 1.11 (1.05, 1.18) |
0.0005 | |
| Ankle Injury/Surgery |
Ipsilateral | 6.31 (4.16, 9.57) |
<0.0001 |
| Ipsilateral (controlled for contralateral predictor) |
3.81 (2.49, 5.84) |
<0.0001 | |
| Contralateral (controlled for ipsilateral predictor) |
2.96 (1.87, 4.70) |
<0.0001 | |
| Contralateral | 5.68 (3.60, 8.95) |
<0.0001 | |
Results adjusted for age, gender and BMI with Generalized Estimating Equations to control for ankle correlation within an individual; CI=Confidence Interval; JSN=joint space narrowing; OST=osteophyte; Knee malalignment defined as degrees deviation from 180° or neutral alignment