. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Exp Eye Res. 2013 Jun 24;0:106–112. doi: 10.1016/j.exer.2013.06.017

Table 1.

Mouse strain genetic backgrounds

Strain	Genotype	Genetic background	Type	Generation^*	Origin	Reference
TSP-1	WT	C57BL/6J	Inbred	-	Jackson Lab	(Lawler et al. 1998)
TSP-1	KO	B6;129S4-Thbs2tm1Bst/J	Congenic	N8 + F13	Jackson Lab	(Lawler et al. 1998)

TSP-2	WT	B6129SF2/J	F2 hybrid	-	Jackson Lab	(Agah et al. 2002)
TSP-2	KO	B6;129S4-Thbs2tm1Bst/J	Targeted mutation	F? + 3PN1	Jackson Lab	(Agah et al. 2002)

OPN	WT	C57BL/6J	Inbred	-	Jackson Lab	(Liaw et al. 1998)
OPN	KO	B6;129S-Sparctm1Hwe/J	Congenic	N10 + N2F5	Jackson Lab	(Liaw et al. 1998)

Hevin	WT	B6129SF2/J	F2 hybrid	-	MD Anderson	(Kang et al. 2011)
Hevin	KO	B6;129S6(Cg)-Spp1tm1Blh/J	Congenic	N10	MD Anderson	(Kang et al. 2011)

SPARC	WT	B6129SF2/J	F2 hybrid	-	EH Sage Lab	(Norose et al. 1998)
SPARC	KO	B6;129S2-Thbs1tm1Hyn/J	Targeted mutation	-	EH Sage Lab	(Norose et al. 1998)

the number of generations was provided by Jackson Laboratory.

N: the number of backcross generations.

F: the number of inbreeding generations.

P: the number of generations when a strain was cryopreserved.

?: Unknown number of generations when mouse was obtained.