. Author manuscript; available in PMC: 2014 Jul 1.

Published in final edited form as: Mol Pharm. 2013 May 29;10(7):2642–2652. doi: 10.1021/mp400075f

Table 1.

The contribution of monomer fraction predicted based on dynamic light scattering (DLS) intensity measurements for CH2 and CH2s. Numbers in parentheses denote the average size.

Temp.	Days	Size (nm) CH2	Concentration (mg/mL) CH2	Size (nm) CH2s	Concentration (mg/mL) CH2s	% of Monomer
Temp.	Days	Size (nm) CH2	Concentration (mg/mL) CH2	Size (nm) CH2s	Concentration (mg/mL) CH2s	CH2	CH2s
37° C	0	7.1(17.62)	1.0	4.8(9.052)	1.0	45.5	89
	1	6.9(54.90)	1.5	4.8(42.24)	1.1	17.5	79.8
	3	6.7(49.48)	1.2	5.0(5.514)	1.1	11.9	86.3
	7	5.1(51.20)	1.0	4.9(5.726)	1.0	8.1	84.9
4° C	0	7.1(17.62)	1.0	4.8(9.052)	1.0	45.5	89
	1	6.5(32.96)	1.2	5.3(5.264)	1.0	42.9	89.3
	3	7.1(10.99)	1.2	8.5(9.255)	0.8	55.6	76.5
	7	7.1(75.33)	1.3	5.1(5.187)	1.0	51.6	90.4