Survival of patients stratified by donor KIR2DL1 functional allelic groups. Shown are the overall survival of (A) the entire cohort of 313 transplantation recipients, (B) the 256 patients with malignant disease, (C) the 231 patients with a hematologic malignancy, and (D) the patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) displayed separately after receiving a KIR2DL1-R245 homozygous (RR), KIR2DL1-R245/C245 heterozygous (RC), or KIR2DL1-C245 homozygous (CC) graft. PRR/RC, P value between RR and RC group; PRR,RC/CC, P value comparing RR and RC groups with CC group; ALL:RR, patients with ALL who received an RR donor graft; ALL:RC, patients with ALL who received an RC donor graft; ALL:CC, patients with ALL who received a CC donor graft; AML:RR, patients with AML who received an RR donor graft; AML:RC, patients with AML who received an RC donor graft; AML:CC, patients with AML who received a CC donor graft; P×RR,RC/CC, P value when comparing RR and RC groups with CC group for patients with the diagnosis of AML or ALL as indicated; PRR, PRC, and PCC, P values when comparing ALL and AML patients who received a similar RR, RC, or CC donor graft.