Survival and cumulative incidence (CI) of disease progression stratified by donor KIR2DL1 allelic groups and the presence of HLA-C receptor-ligand mismatch. Shown are the (A) overall survival probability and (B) CI of disease progression or relapse among different groups of patients with hematologic malignancy. Group 1, patients with a KIR2DL1-R245 homozygous (RR) or KIR2DL1-R245/C245 heterozygous (RC) donor and HLA-C receptor-ligand mismatch; group 2, patients with a KIR2DL1 RR or RC donor but not HLA-C receptor-ligand mismatched; group 3, patients who received a KIR2DL1-C245 homozygous (CC) graft with or without HLA-C receptor-ligand mismatch. Pgroup 1/group 3, P value between group 1 and group 3; Pgroup 2/group 3, P value between group 2 and group 3.