Figure 1. Spatial memory performance.
A) Latency to find the hidden platform. LPS-infused controls and Aged controls were impaired (*p < 0.001) compared to young aCSF-infused rats. The performance of Aged rats improved across days only when treated with Ril (†t = 0.035). B) Distance. LPS controls swam a greater distance than aCSF controls and Aged controls (*p ≤ 0.036). C) Swim Speed. Aged rats swam the most slowly (*p ≤ 0.001). D) Thigmotaxis. Aged controls spent the greatest percentage of time within the pool perimeter (*p < 0.001). E) Probe Trial. Both LPS and Aged groups spent less time in the vicinity of the missing platform than aCSF-infused rats (*p ≤ 0.001).